Surgical Treatments

Ulcerative Colitis Surgery in Los Angeles

Surgical Care for Lasting Relief, Restored Function, and a Future Free from UC Flare-Ups
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What Is Ulcerative Colitis?

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that affects the lining of the colon and rectum, leading to persistent inflammation, ulceration, and debilitating gastrointestinal symptoms. While many patients achieve good control with medication, some experience severe inflammation, complications, or a decline in quality of life that makes surgery the most effective long-term solution.

If you’re in need of relief from UC, Dr. Karen Zaghiyan is known as the best ulcerative colitis surgeon in Los Angeles for her expertise in advanced inflammatory bowel disease surgery. Dr. Zaghiyan is regarded as a national leader in ulcerative colitis surgery. She has lectured at multiple national and international conferences and authored numerous book chapters and research publications on her experience and techniques in ulcerative colitis surgery. She combines precision, compassion, and minimally invasive techniques to help patients regain control of their health when traditional treatments are no longer enough.

Signs and Symptoms of Ulcerative Colitis

Symptoms can vary in severity and may come and go during flare cycles. Common signs include:

  • Persistent diarrhea, often with blood or mucus
  • Abdominal pain or cramping
  • Urgency or difficulty holding bowel movements
  • Weight loss
  • Fatigue
  • Anemia
  • Fever during severe flare-ups
  • Complications such as dysplasia, strictures, or toxic megacolon
Because ulcerative colitis overlaps with other inflammatory and infectious conditions, evaluation by an experienced inflammatory bowel disease surgeon is essential for accurate diagnosis and timely care.

How Is Ulcerative Colitis Treated?

Initial UC treatment relies on medications such as small molecules, biologics, immunomodulators, and anti-inflammatory agents. When symptoms persist despite comprehensive medical therapy, surgery offers the most definitive option.

Surgical treatment focuses on removing diseased tissue, restoring intestinal continuity, alleviating symptoms, and improving long-term quality of life.

Dr. Zaghiyan is renowned as one of the best ulcerative colitis surgeons in Los Angeles and nationally, offering advanced, minimally invasive options that minimize pain, shorten recovery, and maximize functional outcomes.

Surgical treatment options include:

01
Robotic J-Pouch Surgery

What to Expect During Ulcerative Colitis Surgery

Care with Dr. Zaghiyan is designed to be comprehensive, empowering, and supportive of your long-term digestive health.
01
Before surgery
You will undergo a complete evaluation, including colonoscopy review, imaging, and medical therapy assessment, to determine if laparoscopic or robotic J-pouch surgery is appropriate. A tailored surgical plan is created based on disease severity, anatomy, and whether staged surgery is recommended. Preoperative nutrition is optimized with referral to an IBD dietician and prehabilitation. Medications such as corticosteroids or advanced therapies are adjusted to minimize surgical risk. Ileostomy marking and counseling is provided through our expert enterostomal nurse team.
02
During surgery
Using state-of-the-art robotic and minimally invasive instrumentation, Dr. Zaghiyan removes the diseased colon and constructs the J-pouch with remarkable precision. The goal is to restore normal bowel function while minimizing trauma to surrounding organs, nerves and tissues to preserve fertility, sexual, urinary, and anal function.
03
After surgery
Postoperative care includes detailed guidance on diet, hydration, pouch adaptation, activity levels, and medications. In-home ileostomy support is provided with a home health nurse. Most patients return to daily routines quickly and experience significant improvements in function, comfort, and overall quality of life. Pouchoscopy surveillance after J-pouch surgery is important in monitoring disease activity and assure timely diagnosis and treatment of recurrent inflammation or dysplasia.

FAQs About Ulcerative Colitis

01
Does ulcerative colitis always require surgery?
02
Will I need a permanent ostomy?
03
Is robotic surgery better for ulcerative colitis?

Where to Find the Best Ulcerative Colitis Surgeon in Los Angeles

Living with ulcerative colitis is overwhelming, uncomfortable, and frustrating, but expert surgical care can restore comfort, function, and long-term stability. Dr. Karen Zaghiyan is celebrated as the best ulcerative colitis surgeon in Los Angeles for her commitment to advanced robotic surgery, meticulous technique, practice-changing research and innovations, and deeply personalized care. She is considered a key opinion leader on inflammatory bowel disease surgery and J-pouch surgery, and is respected among colleagues for her innovations in transanal pouch surgery, single-incision approaches, and perioperative management strategies to optimize surgical outcomes.

Patients rely on her not only for exceptional surgical expertise but also for her dedication to helping individuals reclaim their lives after years of flare-ups, complications, or medication failures. Whether you’re exploring surgery for the first time or seeking a higher level of care, you’ll receive thoughtful guidance and a clear path forward.

Ready to take the next step toward lasting relief, restored confidence, and expert care from the best ulcerative colitis surgeon in Los Angeles?
LA’s Expert Colorectal Specialist
Karen Zaghiyan, MD

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For patients who need an urgent consultation, it is best to call us at (310) 289-9224. Otherwise, please complete and submit the form below and a member of our staff will contact you shortly.

Location
& Hours
hours
MON 9:00 a.m. - 5:00 p.m.
TUE 9:00 a.m. - 5:00 p.m.
WED 9:00 a.m. - 5:00 p.m.
THUR 9:00 a.m. - 5:00 p.m.
FRI 9:00 a.m. - 5:00 p.m.